Wheeless is an unincorporated community in Cimarron County, Oklahoma, United States.

Nearby are the ruins of Camp Nichols, a military encampment on the Santa Fe Trail, which is a National Historic Landmark.

[3] Wheeless is on E0200 Road;[4] the New Mexico border is approximately six miles west.

[5] The closest highway access points are east and then north to Oklahoma State Highway 325 at the curve where that road turns north after running west from Boise City,[4] or west and then south to the very short New Mexico State Road 410, which links to New Mexico State Road 406,[5] about two miles to the west.

[6] The Texhomex bench mark, being the meeting point of Texas, Oklahoma, and New Mexico, is south-southwest of town.