[17] Wheeling High School offers over 200 different courses, many of which are at the AP or dual credit level.

[19] The following AP courses are offered at Wheeling High School: Biology, Calculus AB, Calculus BC, Chemistry, Computer Science A, English Language & Composition, English Literature & Composition, Environmental Science, Human Geography, Physics C, Psychology, Spanish Language & Culture, French Language & Culture, Statistics, Studio Art: 2-D Design, Studio Art: Drawing, United States Government & Politics, United States History, World History, Italian Language & Culture, Computer Science Principles, Microeconomics, and Macroeconomics.

Wheeling High School competes in the Mid-Suburban League (MSL) East Division.

The school sponsors interscholastic sports teams in cheerleading, cross country, golf, poms, soccer, swimming & diving, tennis, volleyball, basketball, bowling, wrestling, lacrosse, track & field, and water polo.

[25] Wheeling High School sponsors many clubs and activities for students, ranging from the arts and literature to cultural and community service.

[27] The WildStang FTC team, "MiniStang", has won the 2007, 2008, and 2009 Illinois State Championship with an undefeated record.

[citation needed] Wheeling High School's congressional debate team is also one of its most prominent clubs.

The team has gone to the National High School Dance Festival 4 times in the last 8 years.