Wiesbaden-Biebrich station is a railway station in the borough of Biebrich in the Hessian state capital of Wiesbaden on the East Rhine Railway from Wiesbaden to Cologne.

It is classified by Deutsche Bahn as a category 6 station.

Biebrich lies in the area served by the Rhein-Main-Verkehrsverbund (Rhine-Main Transport Association, RMV).

Regionalbahn services operate at hourly intervals on the Frankfurt Hauptbahnhof–Neuwied route.

In the rush hour, the service extends to a half-hourly interval.