Fisher Catholic was built in 1971 at a new location north of downtown Lancaster.

[2] In 1986, the William V. Fisher Catholic High School Foundation was formed to promote and provide support for Catholic Education in the Lancaster, Ohio area.

The club goes on the annual March for Life, and advocates for pro-life views locally.

The quiz team won Ohio Academic Competition (OAC) State Championships in 2004 and 2006, NAQT Division II State Championship in 2006, and has won the local In The Know televised quiz bowl tournament in 2001, 2005, 2006 and 2007.

The team finished second in the OAC state finals to Northmont High School in May 2014 and third in the overall NAQT state championship behind Northmont and Dublin Scioto high schools.