Upon returning to the United States, she taught physics and chemistry in the high schools of Berwyn, Ill. and Maryville, Mo.
From 1914 to 1916 she worked in laboratories at Rush Medical College and Illinois Central Hospital in Chicago.
She then took up a Fellowship at the Mayo Clinic in Immunology and pathology in February 1917, where she stayed a staff member until 1924.
[5] Her work on red blood cell survival rates was first published in 1919, which included the theories of the Ashby Technique.
During those 28 years, she published several studies concerning the standardization and relative sensitivity of serologic tests for syphilis.