The Brenner Pass (1,374 m) at the Austro-Italian border divides it into the northern, Austrian Lower Wipp Valley (Unteres Wipptal) and the southern, Italian Upper Wipp Valley (Oberes Wipptal).
South of the border, the Upper Wipp Valley stretches along the Eisack River by way of Sterzing to Franzensfeste.
The Brenner Autobahn (motorway) (A13 in Austria, A22 in Italy) passes through the valley, beginning with the Europa Bridge near Innsbruck.
The proposed Brenner Base Tunnel would remove all long-distance trains from the valley.
Wipptal was politically and culturally united in the County of Tyrol and the Roman Catholic Diocese of Bolzano-Brixen up to the Treaty of St Germain in 1920.