State Trunk Highway 85 (often called Highway 85, STH-85 or WIS 85) is a 23.48-mile (37.79 km) state highway in Pepin, Dunn, and Eau Claire counties in Wisconsin, United States.

WIS 85 runs east–west in west central Wisconsin from Durand to just southwest of Eau Claire.

About midway along the route, the highway passes through Rock Falls, and three miles (4.8 km) further, Caryville, the only two recognizable settlements between the route's termini.

In recent years, the corridor between Rock Falls and Caryville, especially the western side of the highway along the Chippewa River, has seen some suburban development.

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