[1] He has been the host of The Situation Room with Wolf Blitzer since 2005; previously he served as the network's lead political anchor until 2021.

[3][4][5] His parents were Polish Jewish refugees from German-occupied Poland who survived the Nazi concentration camps; his grandparents, two uncles, and two aunts on his father's side were all murdered in Auschwitz.

[6][7] His maternal grandparents were rounded up in Poland and sent to a labor camp to make ammunition for the German war effort, and later died of typhoid fever.

[8] Blitzer began his career in journalism in the early 1970s, in the Tel Aviv bureau of the Reuters news agency.

In 1973, he caught the eye of Jerusalem Post editor Ari Rath, who hired Blitzer as a Washington correspondent for the English-language Israeli newspaper.

[13][14] While at AIPAC, Blitzer's writing focused on Middle East affairs as they relate to United States foreign policy.

[11] In 1985, Blitzer published his first book, Between Washington and Jerusalem: A Reporter's Notebook (Oxford University Press, 1985).

In 1986, he became known for his coverage of the arrest and trial of Jonathan Pollard, a US Navy intelligence analyst who was charged with spying for Israel.

[19] In its review, the Times praised the book as "lucid and highly readable" and called Blitzer's judgment of Israeli officials "harsh but fair".

In 1998, he began hosting the CNN Sunday morning interview program Late Edition with Wolf Blitzer, which was seen in over 180 countries.

Blitzer will remain hosting documentaries and serving "as principal anchor for all major breaking news.

In 1994, American Journalism Review cited him and CNN as the readers' choice for the Best in the Business Award for network coverage of the Clinton administration.

On May 20, 2007, Blitzer was awarded the honorary Doctorate of Humane Letters by the George Washington University at their undergraduate commencement exercise.

[31] On May 23, 2010, Blitzer was awarded the honorary Doctorate of Humane Letters by Niagara University at their undergraduate commencement exercise.

He also makes a brief cameo in the 2016 movie Batman v Superman: Dawn of Justice,[45] in Mission: Impossible – Fallout (2018),[46][47] and in an episode of Ben 10: Omniverse.

[48] Blitzer played a prominent supporting role in the 2009 documentary Back Door Channels: The Price of Peace, in which he relayed his experiences as a journalist working for the Jerusalem Post, which traces the confluence of factors that made the 1979 Peace Treaty between Israel and Egypt possible.