Wolf Creek is a stream in eastern St. Francois County in the U.S. state of Missouri.
The stream headwaters arise just northeast of Farmington at 37°47′32″N 90°22′19″W / 37.79222°N 90.37194°W / 37.79222; -90.37194 at the confluence of Camp Creek and Taylor Branch.
The stream flows south passing under Missouri Route 32.
[1][2] Wolf Creek was so named due to the presence of wolves in the area.
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