Wolfgang Patsch (born 10 August 1946) is an Austrian physician, specialized in internal medicine/laboratory medicine and a professor in the Department of Pharmacology and Toxicology at the Paracelsus Private Medical University of Salzburg.
Using zonal ultracentrifugation methods developed by Josef R. Patsch (and in collaboration with him), a detailed physical and chemical description of very low-density and high-density lipoproteins was completed.
[8][9] In a collaborative effort with Josef R. Patsch and Antonio M. Gotto, the strong predictive value of the magnitude of postprandial lipemia for coronary heart disease was established.
As atherosclerotic disease is often asymptomatic for many years, knowledge about the quantitative importance of risk factors is essential to effectively manage the disorder and reduce its life-threatening sequels.
ARIC investigators ascertained the effect size of numerous established and candidate risk factors in well characterized populations using the intima-media thickness of the common carotid arteries as surrogate marker for atherosclerosis and cardiovascular endpoints as outcomes.
A main research focus was PGC-1alpha, a transcriptional co-activator that orchestrates several biological programs including mitochondrial biogenesis.
Other genetic factors with relevance for obesity, type 2 diabetes and the metabolic syndrome also were studied in collaboration with H. Esterbauer, H. Oberkofler, T. Felder and F.