It rises near Lydiard Millicent in Wiltshire in the west of England and flows in a generally westerly direction, joining the Avon below Malmesbury.

The Woodbridge Brook rises at Midgehall Copse, just north of the M4 motorway, in the parish of Lydiard Millicent.

It flows first in a northerly direction, and then to the west through Webbs Wood, passing to the north of Brinkworth.

The stream now flows almost due south to Crab Mill Farm and then turns west again to join the Bristol Avon, just above Cowbridge to the east of Malmesbury.

[citation needed] The brook has a mean flow of 20.5 cubic feet per second (0.58 m3/s) as recorded by the Environment Agency gauging station at Crabb Mill.