He was famed for leading a group of his captors up to the Confederate lines, where he then marched them to headquarters as his own prisoners.

In 1867, Captain Wynne moved to St. Francis County, Arkansas, and joined the finance company of Dennis & Beck.

From 1880 to 1885, as the St. Louis, Iron Mountain, and Southern Railroad was under construction, active steamboat riverports like Wittsburg, at that time the county seat of Cross County, were deserted for the railroads.

The location of the settlement of Wynne was first chosen in 1882, when a train derailed, leaving one boxcar without wheels and off the tracks.

On Friday, March 31, 2023, shortly after 4:30 P.M., an intense EF3 tornado with winds reaching 150 miles per hour struck the community.

Numerous homes and businesses, including Wynne High School, were damaged or destroyed.

[5] Wynne lies in south-central Cross County along the boundary between two distinct geographical areas of Arkansas: the fertile farmland of the Arkansas Delta (which is a part of the larger Mississippi Alluvial Plain), and Crowley's Ridge, a distinct rise marking the New Madrid Fault Line.

[6] The climate in this area is characterized by hot, humid summers and generally mild to cool winters.

[7] As of the 2020 United States Census, there were 8,314 people, 3,104 households, and 2,052 families residing in the city.

Wynne also has a branch of the East Arkansas Community College located on Falls Boulevard.

The New Hope School was one of the original buildings constructed to serve students of District 25.

It was donated in 2007 to the Cross County Historical Society where it was restored to its original appearance.