Wyoming Highway 151 (WYO 151) is a 9.89-mile-long (15.92 km) Wyoming State Road, known as LaGrange Road, that is located in extreme southeastern Goshen County.

WYO 151 runs east–west from US 85 west of LaGrange to the Nebraska-Wyoming State Line.

[2][3] Mileposts along WYO 151 increase from west to east.

Wyoming Highway 151 passes through La Grange between Mileposts 3.84 and 4.34.

[3] The entire route is in Goshen County.