[2] Highway 295 crosses the Shoshone River just north of Willwood, and reaches the southern city limits of Powell at just over 12 miles.

Here Highway 295 turns west to join US 14A for quick one block concurrency before leaving US 14A to head north on N. Absaroka Street.

Past the airport, WYO 295 gently turns slightly to the north-northwest and will reach its northern terminus in Elk Basin after 29.35 miles (47.2 km).

Elk Basin is an active oil field with hundreds of derricks operating in it.

The roadway continues northward as Park County Route 1NG to the Montana state line.