[3] Highway 372 travels northwesterly, roughly paralleling the Green River, although from a considerable distance.

Nearing 21 miles, Highway 374 passes along the western side of the Seedskadee National Wildlife Refuge.

Shortly thereafter the western terminus of Wyoming Highway 28 is intersected and acts the main route to Riverton and Lander.

Leaving Fontenelle, WYO 372 heads southwest and then turns west for the last leg of its trip.

[3] In 1994, WYO 372 was reconstructed and widened to accommodate additional traffic due to the mining and oil exploration operations north of Green River.