In the 2004–05 season, Xanthi finished fourth in the Alpha Ethinki (first division, today Super League), the club's all-time best performance.

On September 19, 2022, Xanthi FC announced its withdrawal from the Super League 2 championship, putting an end to its presence in the professional categories, as it failed to address the financial and administrative problems it was facing.

In June 1967, with the Greek military junta in government, the movements in Xanthi were also made to create a team that would unite the dynamics of the two clubs, while the national championships were reorganized.

Not long ago, from 1967 until 1985, the club remained in the Beta Ethniki, with all the restructuring that had suffered the class and benefited in the early years.

From the 8th and 11th places of '87 and '88 respectively, in the summer of 1989 the city and the club lived unforgettable moments by conquering the title of the Beta Ethniki and at the same time the historic rise in the big lounges.

With enthusiasm, passion and a "hot" atmosphere at the stadium, the basic goal of staying in the early years was achieved with a lot of stress.

Mr Kokkala's administration first brought foreign footballers, with the Brazilians Marcelo Veridiano and Sandro making the start and following others.

It was the first provincial club that in 1994 had organized an international tournament at the Xanthi Ground with the participation of Coventry City, Portsmouth and AEK Athens.

[7] In the same year, on 7 July, Xanthi announced one of the biggest transfers in its history, the Brazilian defensive midfielder Emerson.

Since 2021 Xanthi has come in the media spotlight in Australia as Bill Papas who ran Forum Group is alleged to have defrauded 400 million Australian dollars.

Papas stated that he was unable to sell the club or find alternate ways of funding the side for over 9 months.

[16][17] The yellow and black kits of Orfeas[18] and the shades of Aspida,[19] have brought the red of AO Xanthi, which has joined and united the city for many years.

The stadium is located in the same place as the sports center of the Thracian Club, a real jewel for Greek football.

[26] Right next to Xanthi FC Arena, there is the club's athletic center, which, in addition to the two courts, has all the necessary spaces for coaches, players and staff to work on their field.

[27][28] In a huge area almost adjacent to the stadium, it is located in the sports center of Xanthi, with the "despotic" presence of the hotel Le Chalet.

[29] A hotel that after its complete destruction on 7 March 2003 by fire,[30] was not the few who supported, that Christos Panopoulos would leave everything and would be away from the team and generally from football.