Yaqui Pass[1] is a mountain pass on CR S3 in San Diego County in the U.S. state of California.

The pass lies at an elevation of 1,742 ft (531 m)[1] and is located within Anza-Borrego Desert State Park approximately 2 mi (3.2 km) east of the SR 78 and traverses the Santa Rosa Mountains.

Local historians have described the Yaqui Pass route as an "old Indian trail.

"[2] The Yaqui Pass Road CR S3 was built in 1934–35 to connect with the new state highway SR 78 through the Narrows.

[3] During World War II, Yaqui Pass was used by the Marines to get to Camp Ensign, near Clark Dry Lake.