Before pursuing her career in acting, Rughani worked as a stylist for Priyanka Chopra, Esha Gupta, Malaika Arora among others.

[3][4] In 2017, Rughani made her television debut with Jeet Gayi Toh Piya Morey opposite Krip Suri.

[citation needed] After that from May 2018, she played the titular character of a young woman who was ostracized by society due to her mother's profession in Muskaan opposite Sharad Malhotra, a role for which she earned critical acclaim.

[citation needed] In 2020, she started starring as Zara in Sony SAB's fantasy series Hero – Gayab Mode On opposite Abhishek Nigam.

[7] From February 2024 to December 2024, she was playing the lead role of Ibaadat Akhtar Siddiqui opposite Dheeraj Dhoopar in Zee TV's Rabb Se Hai Dua post generation leap.