The duo were discovered by Kawan Prather and signed with his company Ghet-O-Vision, an imprint of LaFace Records to release their debut studio album, Against Da Grain (1999).

J-Bo and Sean Paul met at Decatur's Miller Grove Middle School, where they started the Attic Crew with some friends.

YoungBloodZ has made many appearances in a number of hit singles including Cherish's "Do It to It", Sammie's "You Should Be My Girl", both produced by Jazze Pha.

YoungBloodz have also been featured in songs with T.I., Nelly, Gucci Mane, Lil Scrappy, Twista, DJ Khaled and T-Pain.

[2] YoungBloodZ were arrested on June 1, 2006, on drugs and weapons charges in Atlanta after a traffic stop involving a tour bus with an expired license plate.