Born in Vladimir to a Russian father and a Pontic Greek mother, Lodygin has lived in Greece since 2000, playing for Skoda Xanthi, coming from the youth team.

[2] On 16 June 2019, general director of Zenit Aleksandr Medvedev announced that the club will not offer Lodygin a contract extension for 2019–20 season.

[5] On 18 February 2020, he signed with Russian Premier League club Arsenal Tula until the end of the 2019–20 season.

During his time on PAS Giannina, he managed to establish himself as the first choice keeper immediately after signing, replacing Lefteris Choutesiotis.

[13][14] Due to his winning mentality, character, leadership and great personality, Lodygin was one of the most important players for PAS Giannina on the 2021-22 campaign.

He was called up by Fabio Capello to the Russian squad for the first time on 4 October 2013 for the team's 2014 FIFA World Cup qualification matches against Luxembourg and Azerbaijan.