Estrin began his career as a writer and producer on Charmed, Dawson's Creek, and Tru Calling, before serving as a co-executive producer of Prison Break.

[1][2] He was set to write the script of an ultimately unproduced spin-off, Prison Break: Cherry Hill, along with Prison Break's executive producer Matt Olmstead, both of whom conceived the idea for the spin-off with fellow executive producer, Dawn Parouse.

[4] Estrin was born in Woodland, California, and raised in Brooklyn, New York.

[1] On September 23, 2022, Estrin died while jogging in Hermosa Beach, California, after apparently going into cardiac arrest.

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