He was born in Vartashen (modern Oğuz, Azerbaijan) village of Nukha Uyezd, 1891 to Andria Silikov and Mariam Jeiranov.

In the same year, Silikashvili helped to release of 160 Georgian merchants from Russian prisons, provided them with a wagon, a pass, and returned them to Georgia.

Among the victims of the conflict and persecution was Zinobi Silikashvili's uncle and local cleric, Nikolai Silikov.

[7] Under Silikashvili's leadership and assistance, several factories, a Red Cross medical center, a school, a post office, a cooperative and others were gradually opened in the village of Zinobiani.

Shortly after the migration of the Udis to Georgia, Zinobi Silikashvili led the establishment of the Georgian-Udi Society, the first organizing meeting of which was held on March 25, 1923.

A hearing was held on October 11, 1938, where Silikashvili was sentenced to be shot and his personal property confiscated.