The first version of the Zodiac made up of humans appears in The Avengers #72 (Jan. 1970) and was created by Roy Thomas and Sal Buscema.

[1] The second version of the Zodiac made up of androids first appears in The Defenders #49 (July 1977) and was created by David Anthony Kraft and Keith Giffen.

[2] The third version of the Zodiac made up of humans first appears in the second volume of Alpha Flight and was created by Steven T. Seagle (writer), Scott Clark (penciler), and Chris Carlson (inker).

The original Zodiac group debuts in the title the Avengers[3] and is established as a criminal organization founded and funded by member Cornelius van Lunt (who adopts the identity of Taurus).

Dedicated to economic and political domination of the world, the group uses any means to accomplish this, including subversion; extortion and mass murder.

[4] The character acquires a sentient extradimensional (from the Ankh dimension) artifact called the Zodiac Key, and attempts to assassinate S.H.I.E.L.D.

At this time Aries is team leader, and takes control of the Zodiac Key and acknowledges that Scorpio has redeemed himself for failing to kill Nick Fury.

[6] The title Daredevil features a plan by Zodiac (who are not revealed as the instigators until reappearing in Avengers) to cause civil unrest by inciting a street gang to violence in the borough of Manhattan in New York City.

[11] Member Gemini features in the Savage in the City storyline in the title Astonishing Tales[12] and allies with villain the Plunderer in an attempt to steal the Super Soldier Formula (the same serum that empowers the character Captain America), but is defeated by the jungle hero Ka-Zar.

In the title Avengers, van Lunt reunites the Zodiac (including recruiting a new Aries), and together they plan to attack New York City with a weapon called the Star Blazer.

The group encounter the Avengers once again and after a near defeat, Aries attempts to stage a coup and take power from Taurus.

[14] Zodiac member Aquarius appears in the third volume of the title Ghost Rider,[15] and after learning he has cancer attempts to make a bargain with a demon to save himself.

After creating an android version of the Zodiac, Scorpio kidnaps the hero Nighthawk, hoping to ransom the character as his alter ego is Kyle Richmond, a wealthy entrepreneur.

Taurus escapes and seeks the protection of the West Coast Avengers, who have a series of skirmishes with the androids until the false Zodiac are transported to the Ankh dimension, where they are deactivated.

Taurus, who had vowed to surrender to the authorities once the threat was over, attempted to escape and was killed in a plane crash during a struggle with Avenger Moon Knight.

Hired by Department H, a division of the Canadian military, to test Alpha Flight in battle, the group is murdered by mutant task force Weapon X.

Mockingbird told Nick Fury, Jr. that the Zodiac broke into Parker Industries' Shanghai branch and stole some servers which would allow them to hack into the Webware devices.

The Zodiac thugs blow up a car, destroying the road, but as they gloat the Spider-Mobile tails them, driving along the underside of the overpass.

Cheered on by the citizens of Shanghai, Spider-Man switches the steering over to Mockingbird and opens the roof, addressing his fans in Mandarin, which he picked up taking his driving lessons.

Spider-Man jumps onto the hood of their car, displaying a couple of the new webbing types he developed: micro-coiled Z-metal "Bug Zappers" capable of being electrified, and shock-absorbing expanding web-foam.

Disguised as Spider-Man, Hobie intervenes and Peter tells Sajani to help the wedding guests (who are former Horizon Labs employees) find cover.

When Aries asks if he wants the best and brightest or red shirts, Scorpio states cannon fodder will suffice and that if they want results, they cannot care about the risks.

Scorpio is using the Zodiac Key to look for his price when Spider-Man, the Human Torch, Mockingbird and the Prowler crash through a window and the heroes and various S.H.I.E.L.D.

Scorpio tells him that the game is over now, meaning he has no use for his pawns and uses a Webware to activate the venom samples in all of the Zodiac members.

While Spider-Man called his allies, Scorpio crashed the transmission stating that he will use his influence on Parker Industries enough to have it sink into the ground.

At the Royal Observatory, Scorpio places the Zodiac Grand Orrery in the prime meridian there and performed a ritual that opened a secret passageway underground.

When Scorpio steps into the door, he sees a year filled with events like Skyspear, Norman Osborn's latest activity, Regent's plot, the "New U" device, Doctor Octopus' return, and another superhuman civil war, and the rise of the monsters.

[34] A solo character called Zodiac stars in a self-titled limited series as part of the Dark Reign storyline.

He recruits members that fill out different nations and organizations with the intent to perform certain missions in exchange for special acquirements that could be used for their personal battles.

The rest of the Zodiac members consisted of Cornelius Van Lunt (Taurus), Nick Fury (Gemini), Jake Fury (Scorpio), Dum Dum Dugan (Libra), John Garrett (Aquarius), Daniel Whitehall (Leo), Wolfgang von Strucker (Sagittarius), Thomas Davidson (Virgo), Shoji Soma (Pisces), Vasili Dassaiev (Capricorn) and Viktor Uvarov (Cancer).