[1] The character has appeared in numerous media adaptations, and made his cinematic debut in the animated film Spider-Man: Into the Spider-Verse (2018), where he was voiced by Oscar Isaac in its post-credits scene.

[11] In July 2014 Marvel launched a second Spider-Man 2099 series, with Peter David returning as writer, Will Sliney as artist, and Simone Bianchi illustrating the first issue's cover.

[15] Though seemingly arrogant and confident in all walks of life, Miguel is a very private man and trusts almost no one except for Lyla, an AI assistant whom Xina created as a gift for him.

[volume & issue needed] Miguel eventually becomes head of the genetics program of Alchemax, intended to create new controlled super-powered soldiers called "corporate raiders."

But after a human test subject dies during an early experiment, Miguel tells Tyler Stone he wishes to resign from Alchemax and discontinue his genetics research.

Not wishing to be a blackmailed addict, Miguel recalls that he entered his own genetic code into his machine's databanks during initial experiments, using it as a human DNA test sample.

Intending to use this older template of his pure genetic code to write over his current biology and free himself from the Rapture, Miguel sneaks into Alchemax and uses the gene alteration machines on himself.

He is also surprised at the effect his presence has on the people who have been oppressed for so long, particularly his own mother, who ironically also hates the man her eldest son has become yet admires the exploits of Spider-Man 2099.

[19] Later on, Miguel discovers that an arrogant scientist at Alchemax called Jordan Boone is conducting "Virtual Unreality" experiments to create a doorway into another dimension.

[20] In the "Time Flies Saga" that occurs years later in Peter David's Captain Marvel series, it is revealed that the Net Prophet is actually the hero Justice (John Roger Tensen) and that Thanatos is a corrupt version of Rick Jones from Earth-9309.

[21] The first major crossover of Marvel 2099 happens when Miguel and Dana visit Alchemax's floating city "Valhalla" and are startled by the sudden appearance of two men claiming to be Thor and Heimdall, respectively.

Miguel realizes that this temporal anomaly is what will cause the end of the Heroic Age, since where he is in the past is when history tells him all the heroes and much of Earth's culture and technology were wiped out.

The two Spider-Man characters were united to face a major cause of the chaos, a time-traveling female Hobgoblin of the year 2211 (Robin Borne) from the alternative universe of Earth-9500.

[28] Soon after this, a new villain called the Goblin appears and begins a smear campaign against Spider-Man 2099, displaying out-of-context evidence that implies he is actually a tool of the corporations and only pretends to be a hero of the people.

The final volume sees the apparent deaths of Tyler Stone and Miguel's mother at the hands of the Atlanteans, as the Vulture destroys the Alchemax building.

Jettisoned into space, Rogers passes Mjolnir back to Miguel, who is likewise deemed worthy enough to lift and wield the mystical hammer, gaining new power from it.

[volume & issue needed] Secretly aided by Zero Cochrane 2.0 (Ghost Rider 2099), Miguel rules for the next thousand years, ushering in an unprecedented age of enlightenment.

As the Spiders get to work on Daemos' corpse, his reincarnation speaks to them through the cameras, boasting that he can't be contained, Miguel retorts that the energy field will kill him before he breaks free.

The robot then reactivates, causing its right hand and foot to disable Electro and Vulture respectively, before Miguel fires upon Octopus with Kraven's ship, knocking him out cold.

Suddenly, Superior Spider-Man begins destroying the Web of Life and Destiny with Morlun's dagger, attempting to change his fate but only causing further harm to fabric of realities.

Miguel and Gwen Stacy attempt to help the 616 Spiders against Otto, but Peter Parker-616 orders them to return to their respective time lines before the portal maintained by the Great Web closes.

[51] Meanwhile, Roberta Mendez - the Captain America of 2099 - is revealed to have been trapped in the past shortly after the bounty hunter Venture escapes into the present through Miguel's time portal.

He distracts Man Mountain Marko, who was hired by Loraine to stand guard at her room, long enough for Parker Industries to covertly relocate Tempest.

[63] Sonny upgrades Miguel's time portal to allow him to travel to 2019, where he puts an end to the Fist's plans with help from that era's Tempest and their son Gabri, who has taken on the mantle of Spider-Man 2099.

His superhuman agility and dexterity allow him to perform complicated acrobatic and gymnastic maneuvers that would be impossible for even the most highly trained athlete and help him achieve and regain perfect balance even under extraordinary combat situations.

[volume & issue needed] Spinnerets in his forearms enable him to fire an organic adhesive substance from the top of his wrists, usable in a wide variety of ways.

Feeling guilty that he has inflicted the crazed villain onto a parallel Earth, and now afraid of being hunted down since his identity has been exposed, Spider-Man 2099 joins the Exiles in their quest to stop Proteus and leaves his world.

Miguel presides over the Alchemax-sponsored Avengers consisting of Hercules and future versions of Iron Man (Sonny Frisco), Captain America (Roberta Mendez), Black Widow (Tania), and Hawkeye (Max).

[84] When the teams comes into conflict with Defenders consisting of Hulk 2099, Silver Surfer, Valkyrie, Strange, and Roman the Sub-Mariner, Miguel offers them to go legitimate and work for Alchemax.

[87] After gaining his powers, he creates his Spider-Man costume in a 3D printer and helps a time-lost Peter Parker battle Scorpion 2099 (Kron Stone, who was caught in the same accident as Miguel).