The enzyme 1,4-lactonase (EC 3.1.1.25) catalyzes the generic reaction This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds.
It participates in galactose metabolism and ascorbate and aldarate metabolism.
As of late 2007, three structures have been solved for this class of enzymes, with PDB accession codes 2DG0, 2DG1, and 2DSO.
In a study by Chen et al. a 1,4-lactonase was expressed in E. coli and used as a highly efficient biocatalyst for asymmetric synthesis of chiral compounds.
This EC 3.1 enzyme-related article is a stub.