In early March 2022 Colonel Roman Hryshchenko began forming the brigade in Kharkiv.

[2] The first assignment of the brigade was to reinforce army and national guard units defending the city.

[2] As of July 2022, the brigade was holding the front line north and east of the city of Kharkiv.

[4] On 11 September 2022, the brigade's 249th Battalion announced that the village of Borshchova [uk] had come under Ukrainian control.

[5] Two days later, on 13 September, the brigade's 247th Battalion announced that it had captured the villages of Lyptsi, Hlyboke, and Strilecha, amid a Ukrainian counteroffensive in Kharkiv Oblast.