In enzymology, a 15-hydroxyprostaglandin-D dehydrogenase (NADP+) (EC 1.1.1.196) is an enzyme that catalyzes the chemical reaction Thus, the two substrates of this enzyme are (5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate and NADP+, whereas its 3 products are (5Z,13E)-9alpha-hydroxy-11,15-dioxoprosta-5,13-dienoate, NADPH, and H+.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor.
The systematic name of this enzyme class is (5Z,13E)-(15S)-9alpha,15-dihydroxy-11-oxoprosta-5,13-dienoate:NADP+ 15-oxidoreductase.
This enzyme participates in arachidonic acid metabolism.
This EC 1.1.1 enzyme-related article is a stub.