16S rRNA (guanine527-N7)-methyltransferase (EC 2.1.1.170, ribosomal RNA small subunit methyltransferase G, 16S rRNA methyltransferase RsmG, GidB, rsmG (gene)) is an enzyme with systematic name S-adenosyl-L-methionine:16S rRNA (guanine527-N7)-methyltransferase.
[1][2] This enzyme catalyses the following chemical reaction The enzyme specifically methylates guanine527 at N7 in 16S rRNA.