The 16th SS Police Regiment (German: SS-Polizei-Regiment 16) was initially named the 16th Police Regiment (Polizei-Regiment 16) when it was formed in 1942 from existing Order Police (Ordnungspolizei) units for security duties on the Eastern Front.

The regiment was ordered formed on 9 July 1942 in northern Russia.

I Battalion was transferred to Tilsit, East Prussia (now Sovetsk, Kaliningrad Oblast), and was converted into a training unit on 5 February 1943.

It eventually became I Battalion of the 3rd SS Police Regiment and was replaced by a newly formed battalion in July 1944.

[2] The III Battalion's 9th and 10th Companies committed the Pirčiupiai massacre on June 3, 1944.