Skippered by player-manager Frank Chance, the Cubs won the National League pennant with a record of 116–36, a full 20 games ahead of the second-place New York Giants.

[3] In a major upset, the Cubs were beaten by their crosstown counterparts Chicago White Sox in that year's World Series.

Brown finished second in the NL in wins to Joe McGinnity, but his 1.04 ERA set a major league record.

In addition, Mordecai Brown set a major league record with the lowest earned run average attained with at least 250 innings pitched (1.04).

Infielders Other batters Note: Pos = Position; G = Games played; AB = At bats; H = Hits; Avg.