2,4,5-Trimethoxypropiophenone is a natural phenylpropanoid and precursor in the synthesis of α-asarone.

[1] 2,4,5-Trimethoxypropiophenone is a component of several plant species' essential oils.

The chemical has been identified in Piper marginatum,[2] Acorus tatarinowii,[3] and Asarum maximum.

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