2-Chloromethylpyridine is an organohalide that consists of a pyridine core bearing a chloromethyl group.

It is one of three isomeric chloromethylpyridines, along with 3- and 4-chloromethylpyridine.

It is an alkylating agent.

2-Chloromethylpyridine is a precursor to pyridine-containing ligands.

[1][2] 2-Chloromethylpyridine is an analogue of nitrogen mustards, and has been investigated for its mutagenicity.