The 2000 Global Crossing @ The Glen was the 21st stock car race of the 2000 NASCAR Winston Cup Series and the 15th iteration of the event.

It was long known around the world as the home of the Formula One United States Grand Prix, which it hosted for twenty consecutive years (1961–1980), but the site has been home to road racing of nearly every class, including the World Sportscar Championship, Trans-Am, Can-Am, NASCAR Sprint Cup Series, the International Motor Sports Association and the IndyCar Series.

The circuit's current layout has more or less been the same since 1971, although a chicane was installed at the uphill Esses in 1975 to slow cars through these corners, where there was a fatality during practice at the 1973 United States Grand Prix.

[3] Boris Said of Spencer Motor Ventures would set the fastest time in the session, with a lap of 1:12.580 and an average speed of 121.521 mph (195.569 km/h).

[3] Boris Said of Spencer Motor Ventures would set the fastest time in the session, with a lap of 1:11.532 and an average speed of 123.301 mph (198.434 km/h).