On January 24, Jim Haslett, the former head coach of the New Orleans Saints, signed a three-year deal to become the Rams new defensive coordinator.
The remaining picks were LSU DT Claude Wroten, USC TE Dominique Byrd, Stanford LB Jon Alston, Indiana DE Victor Adeyanju, Virginia WR Marques Hagans, Northwestern LB Tim McGarigle, Minnesota Guard Mark Setterstrom, and Missouri Guard Tony Palmer.
[10] With 11:10 left in the first quarter, Alex Smith completed a 56-yard pass to Arnaz Battle, setting up a 32-yard field goal by Joe Nedney.
With 11:28 left in the first quarter of play, Matt Turk kicked a 31-yard punt giving the Cardinals the ball on the Saint Louis 45.
Marc Bulger hit Torry Holt for gains of 42, 26 and 9 yards during the drive, with the final catch ending in a touchdown.
[14][15] With 4:13 left in the fourth quarter, the Cardinals ended a 16-play, 87-yard drive with a 9-yard Edgerrin James run for a touchdown cutting the Rams lead 16–14.
St. Louis distanced themselves, as QB Marc Bulger completed a 16-yard TD pass to rookie TE Joe Klopfenstein.
In the second quarter, Lions QB Jon Kitna and WR Mike Furrey hooked up with each other on two touchdown passes (a 1-yarder and a 10-yarder), but the Rams retook the lead with Wilkins completing a 46-yard field goal.
[19][20] Hoping to keep their three-game winning streak going, the Rams returned home for an NFC West fight with the Seattle Seahawks.
In the second quarter, St. Louis began pulling away, as RB Steven Jackson ran 2 yards for a touchdown and the duo of Bulger and Holt hooked up again with a 10-yard TD pass.
In the third quarter, the Seahawks started to creep back as Hasselbeck completed a 42-yard TD pass to WR Darrell Jackson.
The Seahawks won as Brown kicked a 54-yard field goal as time ran out, giving Seattle a three-game winning streak against St. Louis.
In the third quarter, things started to get ugly for St. Louis as Chargers free safety Marlon McCree returned a fumble 79 yards for a touchdown.
Hoping to rebound from the road loss to the Chargers, the Rams went home for Week 9, as they fought the Kansas City Chiefs in a “Show Me State Showdown”.
In the second quarter, things got worse for the Rams as QB Damon Huard completed a 3-yard TD pass to TE Tony Gonzalez, while kicker Lawrence Tynes nailed a 42-yard field goal.
Trying to end their three-game skid, the Rams flew to Qwest Field for an NFC West rematch with the Seattle Seahawks.
Trying to end a four-game skid, the Rams flew to Bank of America Stadium for a Week 11 fight with the Carolina Panthers.
In the second quarter, Carolina kicker John Kasay made a 40-yard field goal, while QB Jake Delhomme completed a 62-yard TD pass to WR Steve Smith.
In the fourth quarter, Carolina wrapped up the game with DE Mike Rucker sacking QB Marc Bulger in the Rams end zone for a safety.
Trying to end a five-game skid, the Rams went home for an NFC West rematch with their historic rival, the San Francisco 49ers.
he 49ers responded with RB Frank Gore's 12-yard TD run, yet St. Louis got Wilkins to kick a 51-yard field goal as time ran out on the half.
In the third quarter, the 49ers took the lead with QB Alex Smith completing a 1-yard TD pass to TE Eric Johnson for the only score of the period.
In the second quarter, the Rams continued to struggle as QB Matt Leinart completed an 11-yard TD pass to WR Larry Fitzgerald, while kicker Neil Rackers nailed a 23-yard field goal.
Even though St. Louis made another TD, with Bulger completing a 1-yard pass to WR Isaac Bruce, Arizona held on to win.
Coming off their loss to the Cardinals, the Rams stayed at home for a Monday Night fight with the current NFC North champion Chicago Bears.
After a scoreless first quarter, the Rams struck first with QB Marc Bulger completing a 1-yard TD pass to WR Torry Holt, yet the PAT attempt had a botched snap, making it no good.
However, immediately following St. Louis's first score, the Bears took the lead with DB Devin Hester returning a kickoff 94 yards for a touchdown.
Coming off their dominating road win over the Raiders, the Rams played their last home game of the year as they took on the Washington Redskins.
In the first quarter, St. Louis got off to a fast start as free safety Ronald Bartell returned an interception 38 yards for a touchdown.
RB Steven Jackson, who was elected to his first Pro Bowl at the conclusion of the season, led the NFL in 2006 with 2,334 total yards from scrimmage.