The season began on 30 July 2010 and ended on 11 June 2011.
The winter break was scheduled between 6 November 2010 and 5 March 2011.
FK Dukla Prague secured the 2.
[1] Viktoria Žižkov were confirmed as the second team to gain promotion to the Czech First League on 4 June 2011.
[2] Hlučín, finishing last, were the first team to be relegated.