The 2010 Malaysian Open (also known as the 2010 Proton Malaysian Open for sponsorship reasons) was a tennis tournament played on indoor hard courts.

It was the second edition of the Proton Malaysian Open, and was classified as an ATP World Tour 250 Series of the 2010 ATP World Tour.

It took place at the Bukit Jalil Sports Complex in Kuala Lumpur, Malaysia.

The following players received wildcards into the singles main draw The following players received entry from the qualifying draw: Mikhail Youzhny defeated Andrey Golubev, 6–7(7–9), 6–2, 7–6(7–3) František Čermák / Michal Mertiňák defeated Mariusz Fyrstenberg / Marcin Matkowski, 7–6(7–3), 7–6(7–5)