[1] Roger Federer defeated Rafael Nadal, 6–3, 3–6, 6–1 Daniel Nestor / Nenad Zimonjić defeated Mahesh Bhupathi / Max Mirnyi, 7–6(8–6), 6–4 The top eight players (or teams) with the most countable points accumulated in Grand Slam, ATP World Tour and Davis Cup tournaments during the year qualify for the 2010 Barclays ATP World Tour Finals.

If a player doesn't play enough ATP 250 or Challenger events, the World Team Championship is counted in the 250's table (if entered or achieved better results).

The 2010 Barclays ATP World Tour Finals will count as an additional 19th tournament in the ranking of its eight qualifiers at season's end.

Nadal won his first title of the year and his first in 11 months at the Monte-Carlo Rolex Masters where he defeated Fernando Verdasco in the final with a 6–0, 6–1 victory.

[5] Nadal also claimed his home masters tournament, Mutua Madrileña Madrid Open, for the first time, avenging his 2009 final defeat, to Roger Federer with a 6–4, 7–6(5) win.

[10][11] Nadal also earned his 7th title of the year at the Rakuten Japan Open Tennis Championships beating Gaël Monfils 6–1, 7–5.

Roger Federer began the year by winning the Australian Open, his 16th Slam title defeating Andy Murray 6–3, 6–4, 7–6(11) in the final.

[16] He also fell in his next two finals, at the Gerry Weber Open and the Rogers Cup losing to Lleyton Hewitt 3–6, 7–6(4), 6–4[17] (ending his 15 match winning streak over the Australian) and Andy Murray 7–5, 7–5.

[18] Federer then defended his title in the Western & Southern Financial Group Masters, defeating American Mardy Fish 6–7(5), 7–6(1), 6–4.

Federer then broke Sampras' total as he won his 65th career title in the Davidoff Swiss Indoors, outlasting Novak Djokovic 6–4, 3–6, 6–1 in the final.

Djokovic successfully defended a title for the first time at the Barclays Dubai Tennis Championships defeating Mikhail Youzhny 7–5, 5–7, 6–3.

[33] Murray also defeated Roger Federer 6–3, 6–2 in the final to win his second title in the year at the Shanghai Rolex Masters, he also did not drop a set in the tournament.

Berdych was able to make it to his first Grand Slam Semi-finals at the French Open losing to Robin Söderling after earning a victory over Andy Murray in the round of 16.

Andy Roddick began the year in perfect form by winning the Brisbane International defeating Radek Štěpánek 7–6(2), 7–6(7) in the final.

They also won back-to-back Masters 1000 titles in the 2010 Internazionali BNL d'Italia defeating compatriots Isner/Querrey[58] and in the Mutua Madrileña Madrid Open over Nestor/Zimonjic.

[60] They then won their next three tournaments at the Rogers Cup 7–5, 6–3 over Benneteau/Llodra,[61] Western & Southern Financial Group Masters 6–3, 6–4 over Bhupathi/Mirnyi[62] and the last Slam of the year, the US Open defeating the Asian team of Bopanna/Qureshi 7–6, 7–6.

[73] On 14 September, Wimbledon Champions Jürgen Melzer and Philipp Petzschner were announced as the third qualifiers after the team of Rohan Bopanna and Aisam-ul-Haq Qureshi failed to win the US Open.

Lukáš Dlouhý and Leander Paes only won one title in the year the Sony Ericsson Open, where they defeated Bhupathi/Mirnyi in the final 6–2, 7–5.

Łukasz Kubot and Oliver Marach won two titles this year, both coming on clay where they defeated Starace at the Movistar Open over Starace/Zeballos 6–4, 6–0[77] and at the Abierto Mexicano Telcel over Fognini/Starace 6–0, 6–0.

On 13 November, Wesley Moodie and Dick Norman took the last spot after František Čermák and Michal Mertiňák were defeated by Mahesh Bhupathi and Max Mirnyi.

The two had switched places in the ATP World rankings 6 days earlier, after Sodeling won the Paris Masters overtaking Murray by 20 points.

In the third match of the day Daniel Nestor and Nenad Zimonjić played against Wesley Moodie and Dick Norman and won losing just 3 games: 6–2, 6–1.

In the first match of Day 3, Jürgen Melzer and Philipp Petzschner defeated Lukáš Dlouhý and Leander Paes in three sets, winning the deciding one 10–8.

The lowest ranked doubles couple of the tournament, composed by Wesley Moodie and Dick Norman, were the winners of the first match between Łukasz Kubot and Oliver Marach losing only four games: 6–1, 6–3.

Canadian Daniel Nestor and Serbian Nenad Zimonjić defeated Mahesh Bhupathi and Max Mirnyi with a double tiebreak: 7–5 the first, and 7–1 the second and last one.

After a five-minute absence Djokovic returned to court and held serve, Nadal made it five all before gaining the all important break.

[86] The number 1 ranked on doubles Bob and Mike Bryan defeated Lukáš Dlouhý and Leander Paes 6–3, 6–4, and closed their Round robin matches for this tournament.

The first singles semi final saw world number 1 Rafael Nadal face home hero Andy Murray.

The day began with the doubles final between Daniel Nestor and Nenad Zimonjić, who beat top seeds and defending champions Bob and Mike Bryan in the semifinals, versus Mahesh Bhupathi and Max Mirnyi.

The 2008 champions lifted their second title in doubles at the Barclays ATP World Tour Finals after beating 4th seeds in 1 hour and 21 minutes, with 7–6(6), 6–4.