Some of the club's notable achievements included Edson Buddle being a runner-up for the MLS Golden Boot award, with 17 goals tallied during the regular season.

The Galaxy made it to the quarterfinals of the U.S. Open Cup with a convincing 2–0 win over second-tier AC St. Louis, before losing to Seattle Sounders FC by the same score line.

Los Angeles began their fifteenth Major League Soccer regular season at home with a 1–0 win against the New England Revolution on March 27, 2010.

[3] After scoring a league-leading 7 goals, Edson Buddle was named MLS Player of the Month for April[4] After a quick and incredible recovery, David Beckham returns to the LA Galaxy.

Hosting the Saints at Home Depot Center on June 29, a pair of goals from Chris Klein and Juninho gave the Galaxy a 2–0 victory over visiting St. Louis.

In front of a sold-out crowd of 4,500 at Starfire Complex, the Galaxy would lose 2–0, the loss to the eventual champions ended their brief Open Cup campaign.