The 2011–12 EHF Women's Champions League was the nineteenth edition of the EHF Women's Champions League, the top continental handball event for club teams in Europe, organized and supervised by the European Handball Federation.

Larvik HK entered the competition as title holders after beating SD Itxako in past season's final.

[1] Budućnost Podgorica won the title for the first time by defeating Győri Audi ETO KC in the big final.

[2] Following the decision of the Executive Committee of the European Handball Federation in April 2011, the system of the EHF Women's Champions League qualifying tournaments have changed.

Places were distributed according to the EHF league coefficient, which took into account the performances in European competitions from 2007–08 to 2009–10.

The sides played against each other once and the top two teams of each group advanced to the second qualifying phase, where they were classified automatically into the fourth pot.

[6] However, as stated in the EHF regulations, clubs from the same federation enjoyed protection and could not be selected into the same group.