The final was contested in two-legged home-and-away format between two Mexican teams, Santos Laguna and Monterrey.

The winner earned the right to represent CONCACAF at the 2013 FIFA Club World Cup, entering at the quarterfinal stage.

[2] Monterrey won the second leg 4–2 after overcoming a two-goal deficit, winning the final 4–2 on aggregate.

[3][4] For the fourth time in five seasons of the CONCACAF Champions League, the final was played between two Mexican sides.

Santos Laguna finished top of Group 1 ahead of Toronto FC and Águila in the group stage, and were seeded second for the championship stage, where they eliminated Houston Dynamo in the quarterfinals and Seattle Sounders FC in the semifinals.