David Akers made it 7–3 on a 33-yard field goal, though the Lions missed out on seven points that series when a touchdown reception by Calvin Johnson was reversed.
A pass interference penalty by Bill Bentley put the ball on the Lions 1-yard line late in the final quarter, and Arizona's Rashard Mendenhall plunged over two plays later for a touchdown.
The Redskins got a late 21-yard field goal from John Potter to close the gap to 27–20, but could not gain possession on the ensuing onside kickoff.
Set up by a 57-yard punt return from Micheal Spurlock, Matthew Stafford scored first when he recovered his own fumble in the end zone following a 1-yard quarterback sneak.
On the Lions next possession, Reggie Bush scored on a 37-yard TD run, hurdling Bears safety Major Wright on his way to the end zone.
On Chicago's next possession, Ndamukong Suh forced a Jay Cutler fumble, then Nick Fairley scooped up the ball and took it the remaining 4 yards for the score to give Detroit a 37–16 lead.
On a potential clock-killing drive, Lions running back Joique Bell lost a fumble, and the Bears took advantage with another Cutler TD pass – this one going 10 yards to Earl Bennett.
After another successful two-point conversion, Chicago was within one score, 40–32, but Detroit's Kris Durham recovered the ensuing onside kick to preserve the victory.
The Lions were attempting to end a 21-game regular season losing streak at Green Bay's Lambeau Field, but were hampered by injuries to starting wide receivers Nate Burleson and Calvin Johnson, neither of whom could suit up for the game.
Mason Crosby converted field goals of 26 and 52 yards for the Packers, while David Akers hit a 53-yarder for the Lions, making the halftime score 6–3 in favor of Green Bay.
The big blow of the game came just 1:26 later, when Aaron Rodgers found James Jones deep, resulting in an 83-yard touchdown and a 16–3 Green Bay lead.
After a Lions three-and-out, the Browns got the ball with enough time to get Billy Cundiff into field goal range, and he converted a 40-yard attempt to make the halftime score 17–7.
In the third quarter, Stafford hit Reggie Bush on a short pass, and the running back took it 18 yards for a touchdown, bringing Detroit closer at 17–14.
After a key interception of Weeden by DeAndre Levy, the Lions put the game away when Stafford and Fauria connected a third time with a 10-yard TD pass play, providing a final score of 31–17.
The Lions tied the game at 24 in the fourth quarter, when Calvin Johnson leaped up and beat three Bengals defenders in the end zone on a 50-yard pass from Matthew Stafford.
Detroit punter Sam Martin then shanked a punt that netted only 28 yards before going out of bounds at the Cincinnati 49 with 26 seconds left in the game.
The Lions came back with a 1-yard TD run by Reggie Bush, on a drive that featured a key 54-yard pass from Stafford to Calvin Johnson, cutting the lead to 27–24.
The Lions lost the ball on downs with 1:24 left in the game, but Dallas could only take 22 seconds off the clock before Dan Bailey put them up 30–24 with a 44-yard field goal.
The Lions tied the game at 7 later in the first quarter when Matthew Stafford found Kris Durham in the back of the end zone with a 5-yard TD pass.
Josh McCown, who relieved an injured Cutler, led the Bears on a 74-yard TD drive, capped by an 11-yard pass to Brandon Marshall for the score.
Needing a two-point conversion to tie the game, McCown's pass to Dante Rosario sailed out of the end zone, but Detroit's Willie Young was called for roughing the passer, giving the Bears another chance from the 1-yard line.
The Steelers jumped out to an early 14–0 lead, when Ben Roethlisberger hit Antonio Brown with TD passes of 34 and 47 yards on consecutive drives.
Detroit had a chance to go up by 11 in the closing seconds of the first half, but after three incomplete passes from the Steelers' 1-yard line, they settled for a 19-yard Akers field goal to make the score 27–20.
The Lions got inside the Pittsburgh 10-yard line on their next possession, but failed to score on three straight plays before calling in the field goal unit.
Late in the half, Leonard Johnson picked off a Stafford pass intended for Brandon Pettigrew and returned it 48 yards for a touchdown, sending the Bucs to the locker room with a 17–14 lead.
Despite three turnovers and a missed field goal in the first half, the Lions rebounded to dominate the Packers, earning their first win on Thanksgiving Day since 2003.
After David Akers and Mason Crosby exchanged field goals, Green Bay took their first and only lead of the day in the second quarter when Nick Perry forced a Matthew Stafford fumble that Morgan Burnett returned for a 1-yard touchdown.
Playing against the Ravens, Detroit rallied in the first quarter before Baltimore's Justin Tucker kicked three field goals to give his team a halftime lead, 9–7.
As the clock ran out with the score tied, Head Coach Jim Schwartz decided to let the game go into overtime despite Detroit possessing two timeouts.
With both teams resting injured superstars (Adrian Peterson for Minnesota and Calvin Johnson for Detroit), the Vikings won the low-scoring contest, 14–13.