The 2015–16 Euroleague Regular Season was played from 15 October to 18 December 2015.
A total of 24 teams competed in the group stage to decide the 16 places in the Top 16.
In each group, teams played against each other home-and-away in a round-robin format.
Pınar Karşıyaka and Darüşşafaka Doğuş made their debut appearances in the group stage of the modern era of Euroleague Basketball.
If teams are level on record at the end of the Regular Season, tiebreakers are applied in the following order: