The Cardinals were eliminated from playoff contention for the first time since 2013 in Week 15 after a loss to the New Orleans Saints.

Because the Chicago Cubs won the 2016 World Series, their first title in 108 years, the Cardinals also finished the season with the longest active championship drought in the four major American professional sports, with their last championship in 1947 as the Chicago Cardinals.

Notes Front office Head coaches Offensive coaches Special teams coaches Strength and conditioning Running backs (RB) Wide receivers (WR) Tight ends (TE) Defensive linemen (DL) Defensive backs (DB) Special teams Reserve Note: Intra-division opponents are in bold text.

With Patriots quarterback Tom Brady suspended and Jimmy Garoppolo starting, the Cardinals were huge favorites to win.

The game was close, but was lost last minute, with a missed game-winning Cardinals field goal.

Despite losing running back David Johnson to a knee injury in the first quarter, Arizona still managed to blow out the Rams, 44-6 to finish the year at 7-8-1.