The 2016 season was the Philadelphia Eagles' 84th in the National Football League (NFL) and their first under head coach Doug Pederson.

The Eagles named 2nd overall pick Carson Wentz the starting quarterback for Week 1 against the Cleveland Browns.

The Browns would respond early in the 2nd quarter with an Isaiah Crowell 1 yard TD to cut the Eagles lead to 10–7.

Midway through the 3rd Quarter, a bad snap by Browns center Cameron Erving went over the head of Quarterback Robert Griffin III and into the end zone for a safety and it extended the Eagles lead to 15–10.

Following their big win at home, the Eagles trailed to Illinois to square off Jay Cutler and the Bears in Soldier Field.

Cutler fumbled early in the 3rd quarter, setting up a Ryan Mathews 3-yard touchdown to increase the Eagles lead to 16–7.

On the Bears' next drive, Cutler threw an interception to Linebacker Nigel Bradham to set up a touchdown from Carson Wentz to tight end Trey Burton to increase their lead to 22–7.

The Eagles returned home to face their long time state rivals, the Pittsburgh Steelers.

Early in the 2nd quarter, Rookie Quarterback Carson Wentz threw a 12-yard touchdown to Jordan Matthews to add to their lead.

Then, early in the 2nd Half, Wentz threw a 73-yard touchdown to running back Darren Sproles to extend their lead to 20–3.

After a Steelers 3 and out, rookie running back Wendell Smallwood scored his first career rushing touchdown and it extend to Eagles lead to 27–3.

Roethlisberger threw an interception to Rodney McLeod late in the game as the Eagles pulled away a huge 34–3 win.

With the win, The Eagles headed into their bye week with a commanding 3–0 record and 1st place in NFC East.

Wentz threw 2 interceptions and the defense allowed 2 touchdowns by Eli Manning to Odell Beckham Jr and to Roger Lewis.

Despite a rushing touchdown by Carson Wentz in the final seconds, they failed the 2-point conversion; sealing a fifth straight loss and a playoff elimination.

After a heartbreaking loss that knocked the Eagles out of the playoffs, they came back home to square off the New York Giants for round 2.

With the win, the Eagles snapped their 5-game losing streak and won against the Giants at home for the 3rd consecutive season.