The 2017–18 Mississippi Valley State Delta Devils basketball team represented Mississippi Valley State University in the 2017–18 NCAA Division I men's basketball season.

The Delta Devils, led by fourth-year head coach Andre Payne, played their home games at the Harrison HPER Complex in Itta Bena, Mississippi as members of the Southwestern Athletic Conference.

Due to the ineligibility of Grambling State, the Delta Devils received the No.

8 seed in the SWAC tournament and lost to Arkansas–Pine Bluff in the quarterfinals.

In the SWAC tournament, they lost to Alcorn State in the quarterfinals.