The 2018 Copa do Brasil second stage was the second stage of the 2018 Copa do Brasil football competition.
[1] A total of 40 teams competed in the second stage to decide twenty places in the third stage of the 2018 Copa do Brasil.
[2] In the second stage, each tie was played on a single match basis.
If tied, extra time would not be played and the penalty shoot-out would be used to determine the winner.
[2] Host teams were settled in the first-stage draw.