[1] A total of 16 teams competed in the final stages to decide the champions of the 2018 Copa do Brasil.
If tied on aggregate, the away goals rule would not be used, extra time would not be played and the penalty shoot-out would be used to determine the winner.
[2] The draw for the round of 16 was held on 20 April 2018, 11:00 at CBF headquarters in Rio de Janeiro.
The draw for the quarter-finals was held on 30 May 2018, 11:00 at CBF headquarters in Rio de Janeiro.
The draw to determine the home-and-away teams for both legs was held on 22 August 2018, 11:00 at CBF headquarters in Rio de Janeiro.
The draw to determine the home-and-away teams for both legs was held on 27 September 2018, 14:30 at CBF headquarters in Rio de Janeiro.