Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.

Source: Competitions During the break for the 2018 FIFA World Cup, Palmeiras disputed three friendly matches, two in Panama and one in Costa Rica.

The draw for the round of 16 was held on 4 June 2018, 20:00 PYT (UTC−4), at the CONMEBOL Convention Centre in Luque, Paraguay.

[46] As a team that disputed the Copa Libertadores, Palmeiras entered in the round of 16.

[48] A draw was held on August 22, 2018 to define the order of the matches.