It was also their first season under head coach Frank Reich and second under the leadership of general manager Chris Ballard.

Despite a 1–5 start, the Colts managed to improve on their injury-plagued 4–12 campaign from the year prior with a 38–10 victory over the Tennessee Titans, and a 5-game winning streak.

[1] On December 31, 2017, the Colts parted ways with head coach Chuck Pagano, who had led the team for six seasons.

However, one day later, McDaniels unexpectedly withdrew from the agreement in principle to become the Colts' head coach.

[3][4] On February 11, 2018, after interviewing multiple candidates, including Leslie Frazier and Dan Campbell, the Colts announced the hiring of Frank Reich, formerly the Philadelphia Eagles' offensive coordinator.

Running backs (RB) Wide receivers (WR) Tight ends (TE) Defensive linemen (DL) Defensive backs (DB) Special teams Reserve The Colts' 2018 schedule was announced on April 19.

However, while driving down the field, Jack Doyle lost a fumble which was returned 83 yards for a touchdown, putting the game away.

In a rain-filled affair, the Colts were unable to nurse a late lead, as they lost to the defending champion Eagles 20-16 and fell to 1–2.