The 2018 Jackson State Tigers football team represented Jackson State University in the 2018 NCAA Division I FCS football season.

The Tigers were led by second-year head coach Tony Hughes and played their home games at Mississippi Veterans Memorial Stadium in Jackson, Mississippi as members of the East Division of the Southwestern Athletic Conference (SWAC).

During the SWAC football media day held in Birmingham, Alabama on July 13, 2018, the Tigers were predicted to finish third in the East Division.

[1] They did not have any players selected to any of the Presason All-SWAC Teams.